SOLUTION C19-MC™

The Distinctive
Biology of Placenta.
For Research.

SOLUTION C19-MC™ is a placenta-derived exosome preparation developed for advanced life science research.

For Research Use Only (RUO)Made in Japan
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Placenta-Derived

Derived from carefully sourced human placental material.

C19MC MicroRNAs

Exploring a distinctive miRNA signature associated with human placental biology.

Made in Japan

Produced in Japan under controlled processing and quality management.

For Research Use Only

Intended for research use in North America.

Why Placenta?

Human placenta is a highly specialized temporary organ that supports communication, adaptation, and development throughout pregnancy.

Its distinctive biology has made the placenta an important subject of research in extracellular vesicles and regulatory microRNAs.

Dynamic Biological Communication
Extracellular Vesicles
Distinctive miRNA Biology

The C19MC miRNA Cluster

A distinctive miRNA signature of placental biology.

C19MC, the chromosome 19 microRNA cluster, is one of the largest miRNA gene clusters in the human genome.

It is highly expressed in human placenta, particularly in trophoblasts, and C19MC miRNAs have been identified in extracellular vesicles released by placental trophoblasts.

Why Does This Biology Matter?

Placenta-associated extracellular vesicles and regulatory microRNAs are studied for their roles in intercellular communication and cellular regulation.

01

Paracrine Signaling

Intercellular communication through locally acting biological signals.

02

Cellular Homeostasis

Biological processes involved in maintaining cellular balance and function.

03

Mitochondrial Biology

Cellular processes associated with mitochondrial status and function.

04

Autophagy / Mitophagy

Quality-control pathways involved in cellular and mitochondrial homeostasis.

Biological Origin → Molecular Composition → Biological Responses

70+ Years of
Placenta Heritage

The scientific foundation of C19-MC is rooted in decades of placenta-related research and manufacturing experience.

Japan Bio Products Co., Ltd. (JBP) has built on a legacy of placenta-related expertise dating back to its predecessor organization in 1954.

Today, JBP provides the placental source material used for SOLUTION C19-MC™, bringing this long-standing expertise into its role in the C19-MC research product.

Predecessor foundation established
Manufacturing approval for Laennec
Japan Bio Products Co., Ltd. established
Placental source material for SOLUTION C19-MC™

Quality, Made in Japan.

From placental source material to cell processing and quality management, SOLUTION C19-MC™ is produced through a controlled process in Japan.

Placental Source MaterialProvided by Japan Bio Products (JBP).
Culture / Cell ProcessingPerformed by ONODERA Medical in Japan.
Quality ManagementControlled processing, testing, and frozen storage are integral to the product's quality management process.

Made in Japan. Built for Global Research.

SOLUTION C19-MC™

Placenta. Science. Japan.

Explore the biological origin, molecular characteristics, characterization data, quality process, safety testing, and product specifications of SOLUTION C19-MC™.

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SOLUTION C19-MC research-use product

CONTACT

Let’s Explore
What’s Next in Research.

For product information, research-use inquiries, purchasing, or distribution inquiries, please contact us.

✉   info@nodegraf.com

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